TNFAIP8L2 polyclonal, anti-mouse
€388.00
In stock
SKU
BS72144
Background:
TNFα-IP 8L2 (tumor necrosis factor, α-induced protein 8-like 2), also known as TIPE2, is a 184 amino acid protein that shares 94% identity with its mouse counterpart and belongs to the TNFAIP8 family. Expressed in spleen, thymus, small intestine and lymph node with lower levels present in colon, lung and skin, TNFα-IP 8L2 plays a role in maintaining immune homeostasis, specifically by acting as a negative regulator of both innate and adaptive immunity. In addition, TNFα-IP 8L2 functions as a negative regulator of T cell receptor function and is thought to promote FAS-induced apoptosis. The gene encoding TNFα-IP 8L2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Alternative Name:
TIPE2
Application Dilution: WB: 1:500 - 1:2000
Specificity: TNFAIP8L2 polyclonal antibody detects endogenous levels of TNFAIP8L2 protein.
Immunogen:
Recombinant protein of human TNFAIP8L2
MW: 20kDa
Swis Prot.: Q6P589
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
TNFα-IP 8L2 (tumor necrosis factor, α-induced protein 8-like 2), also known as TIPE2, is a 184 amino acid protein that shares 94% identity with its mouse counterpart and belongs to the TNFAIP8 family. Expressed in spleen, thymus, small intestine and lymph node with lower levels present in colon, lung and skin, TNFα-IP 8L2 plays a role in maintaining immune homeostasis, specifically by acting as a negative regulator of both innate and adaptive immunity. In addition, TNFα-IP 8L2 functions as a negative regulator of T cell receptor function and is thought to promote FAS-induced apoptosis. The gene encoding TNFα-IP 8L2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Alternative Name:
TIPE2
Application Dilution: WB: 1:500 - 1:2000
Specificity: TNFAIP8L2 polyclonal antibody detects endogenous levels of TNFAIP8L2 protein.
Immunogen:
Recombinant protein of human TNFAIP8L2
MW: 20kDa
Swis Prot.: Q6P589
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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