TNFRSF10B antibody (clone 2D6), anti-human
€435.00
In stock
SKU
AC-AT4271a
Catalog Number: AC-AT4271a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IP, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IP, E
Request Information AC-AT4271a">Request Information
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Other Names:
Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2, CD262, TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Antigen Type:
Recombinant Protein
Gene Name: TNFRSF10B
Gene ID: 8795
NCBI Accession: NP_003833.4;NP_671716.2
Primary Accession: O14763
Other Accession: BC001281
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Other Names:
Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2, CD262, TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9
Antigen Type:
Recombinant Protein
Gene Name: TNFRSF10B
Gene ID: 8795
NCBI Accession: NP_003833.4;NP_671716.2
Primary Accession: O14763
Other Accession: BC001281
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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