TNFRSF11B Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13738c
Background:
The protein encoded by this gene is a member of theTNF-receptor superfamily. This protein is an osteoblast-secreteddecoy receptor that functions as a negative regulator of boneresorption. This protein specifically binds to its ligand,osteoprotegerin ligand, both of which are key extracellularregulators of osteoclast development. Studies of the mousecounterpart also suggest that this protein and its ligand play arole in lymph-node organogenesis and vascular calcification.Alternatively spliced transcript variants of this gene have beenreported, but their full length nature has not been determined.
Other Names:
Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TNFRSF11B, OCIF, OPG
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13738c was selected from the Center region of TNFRSF11B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TNFRSF11B
Gene ID: 4982
Primary Accession: O00300
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of theTNF-receptor superfamily. This protein is an osteoblast-secreteddecoy receptor that functions as a negative regulator of boneresorption. This protein specifically binds to its ligand,osteoprotegerin ligand, both of which are key extracellularregulators of osteoclast development. Studies of the mousecounterpart also suggest that this protein and its ligand play arole in lymph-node organogenesis and vascular calcification.Alternatively spliced transcript variants of this gene have beenreported, but their full length nature has not been determined.
Other Names:
Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TNFRSF11B, OCIF, OPG
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13738c was selected from the Center region of TNFRSF11B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TNFRSF11B
Gene ID: 4982
Primary Accession: O00300
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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