TNFRSF8 antibody (clone 3B9), anti-human
€435.00
In stock
SKU
AC-AT4283a
Catalog Number: AC-AT4283a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT4283a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: E
Request Information AC-AT4283a">Request Information
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Other Names:
Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E
Antigen Type:
Recombinant Protein
Gene Name: TNFRSF8 (HGNC:11923)
Gene ID: 943
NCBI Accession: NP_001234.2;NP_001268359.1
Primary Accession: P28908
Other Accession: NM_001243
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Other Names:
Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E
Antigen Type:
Recombinant Protein
Gene Name: TNFRSF8 (HGNC:11923)
Gene ID: 943
NCBI Accession: NP_001234.2;NP_001268359.1
Primary Accession: P28908
Other Accession: NM_001243
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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