TNFSF12 antibody (clone 4H3), anti-human, mouse
€435.00
In stock
SKU
AC-AT4285a
Catalog Number: AC-AT4285a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, Ehttps://www.abcepta.com/products/pdf_download/AT4285a-TNFSF12-Antibody-monoclonal-M01">Request Information AC-AT4285a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, Ehttps://www.abcepta.com/products/pdf_download/AT4285a-TNFSF12-Antibody-monoclonal-M01">Request Information AC-AT4285a">Request Information
Background:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Other Names:
Tumor necrosis factor ligand superfamily member 12, APO3 ligand, TNF-related weak inducer of apoptosis, TWEAK, Tumor necrosis factor ligand superfamily member 12, membrane form, Tumor necrosis factor ligand superfamily member 12, secreted form, TNFSF12, APO3L, DR3LG
Antigen Type:
Recombinant Protein
Gene Name: TNFSF12
Gene ID: 407977;8742
NCBI Accession: NP_003800.1;NP_742086.1
Primary Accession: O43508
Other Accession: BC019047
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Some transcripts that skip the last exon of this gene and continue with the second exon of the neighboring TNFSF13 gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Other Names:
Tumor necrosis factor ligand superfamily member 12, APO3 ligand, TNF-related weak inducer of apoptosis, TWEAK, Tumor necrosis factor ligand superfamily member 12, membrane form, Tumor necrosis factor ligand superfamily member 12, secreted form, TNFSF12, APO3L, DR3LG
Antigen Type:
Recombinant Protein
Gene Name: TNFSF12
Gene ID: 407977;8742
NCBI Accession: NP_003800.1;NP_742086.1
Primary Accession: O43508
Other Accession: BC019047
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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