TNNC1 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13841a
Background:
Troponin is a central regulatory protein of striatedmuscle contraction, and together with tropomyosin, is located onthe actin filament. Troponin consists of 3 subunits: TnI, which isthe inhibitor of actomyosin ATPase; TnT, which contains the bindingsite for tropomyosin; and TnC, the protein encoded by this gene.The binding of calcium to TnC abolishes the inhibitory action ofTnI, thus allowing the interaction of actin with myosin, thehydrolysis of ATP, and the generation of tension. Mutations in thisgene are associated with cardiomyopathy dilated type 1Z. [providedby RefSeq].
Other Names:
Troponin C, slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13841a was selected from the N-term region of TNNC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TNNC1
Gene ID: 7134
Primary Accession: P63316
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Troponin is a central regulatory protein of striatedmuscle contraction, and together with tropomyosin, is located onthe actin filament. Troponin consists of 3 subunits: TnI, which isthe inhibitor of actomyosin ATPase; TnT, which contains the bindingsite for tropomyosin; and TnC, the protein encoded by this gene.The binding of calcium to TnC abolishes the inhibitory action ofTnI, thus allowing the interaction of actin with myosin, thehydrolysis of ATP, and the generation of tension. Mutations in thisgene are associated with cardiomyopathy dilated type 1Z. [providedby RefSeq].
Other Names:
Troponin C, slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13841a was selected from the N-term region of TNNC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TNNC1
Gene ID: 7134
Primary Accession: P63316
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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