TNNI2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP16030a
Background:
This gene encodes a fast-twitch skeletal muscle protein, amember of the troponin I gene family, and a component of thetroponin complex including troponin T, troponin C and troponin Isubunits. The troponin complex, along with tropomyosin, isresponsible for the calcium-dependent regulation of striated musclecontraction. Mouse studies show that this component is also presentin vascular smooth muscle and may play a role in regulation ofsmooth muscle function. In addition to muscle tissues, this proteinis found in corneal epithelium, cartilage where it is an inhibitorof angiogenesis to inhibit tumor growth and metastasis, and mammarygland where it functions as a co-activator of estrogenreceptor-related receptor alpha. This protein also suppresses tumorgrowth in human ovarian carcinoma. Mutations in this gene causemyopathy and distal arthrogryposis type 2B. Alternatively splicedtranscript variants have been found for this gene. [provided byRefSeq].
Other Names:
Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform, TNNI2
Gene Name: TNNI2
Gene ID: 7136
Primary Accession: P48788
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a fast-twitch skeletal muscle protein, amember of the troponin I gene family, and a component of thetroponin complex including troponin T, troponin C and troponin Isubunits. The troponin complex, along with tropomyosin, isresponsible for the calcium-dependent regulation of striated musclecontraction. Mouse studies show that this component is also presentin vascular smooth muscle and may play a role in regulation ofsmooth muscle function. In addition to muscle tissues, this proteinis found in corneal epithelium, cartilage where it is an inhibitorof angiogenesis to inhibit tumor growth and metastasis, and mammarygland where it functions as a co-activator of estrogenreceptor-related receptor alpha. This protein also suppresses tumorgrowth in human ovarian carcinoma. Mutations in this gene causemyopathy and distal arthrogryposis type 2B. Alternatively splicedtranscript variants have been found for this gene. [provided byRefSeq].
Other Names:
Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform, TNNI2
Gene Name: TNNI2
Gene ID: 7136
Primary Accession: P48788
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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