TNNI3 antibody (clone 10000000), anti-human
€435.00
In stock
SKU
AC-AT4292a
Catalog Number: AC-AT4292a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT4292a">Request Information
Background:
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Other Names:
Troponin I, cardiac muscle, Cardiac troponin I, TNNI3, TNNC1
Antigen Type:
Recombinant Protein
Gene Name: TNNI3
Gene ID: 7137
NCBI Accession: NP_000354.4
Primary Accession: P19429
Other Accession: NM_000363
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Other Names:
Troponin I, cardiac muscle, Cardiac troponin I, TNNI3, TNNC1
Antigen Type:
Recombinant Protein
Gene Name: TNNI3
Gene ID: 7137
NCBI Accession: NP_000354.4
Primary Accession: P19429
Other Accession: NM_000363
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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