TNNT2 (clone 4B1D5), anti-human

Background:
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Research Area: Signal Transduction

Synonyms: CMH2, RCM3, TnTC, cTnT, CMD1D, CMPD2, LVNC6

Immunogen: Purified recombinant fragment of human TNNT2 (AA: 1-295) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage