TNXB antibody (clone 2D3-1B10), anti-human
€435.00
In stock
SKU
AC-AT4296a
Catalog Number: AC-AT4296a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IP, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IP, E
Request Information AC-AT4296a">Request Information
Background:
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Tenascin-X, TN-X, Hexabrachion-like protein, TNXB, HXBL, TNX, TNXB1, TNXB2, XB
Antigen Type:
Recombinant Protein
Gene Name: TNXB (HGNC:11976)
Gene ID: 7148
NCBI Accession: NP_061978.6;NP_115859.2
Primary Accession: P22105
Other Accession: BC033740
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Tenascin-X, TN-X, Hexabrachion-like protein, TNXB, HXBL, TNX, TNXB1, TNXB2, XB
Antigen Type:
Recombinant Protein
Gene Name: TNXB (HGNC:11976)
Gene ID: 7148
NCBI Accession: NP_061978.6;NP_115859.2
Primary Accession: P22105
Other Accession: BC033740
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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