Tollip polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6938
Background:
Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-κB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the Toll/Interleukin-1 receptor (TIR) domain.
Alternative Name:
Toll-interacting protein, TOLLIP
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: TOLLIP polyclonal antibody detects endogenous levels of TOLLIP protein.
Immunogen:
Recombinant full length Human Tollip.
MW: ~ 33 kDa
Swis Prot.: Q9H0E2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-κB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the Toll/Interleukin-1 receptor (TIR) domain.
Alternative Name:
Toll-interacting protein, TOLLIP
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: TOLLIP polyclonal antibody detects endogenous levels of TOLLIP protein.
Immunogen:
Recombinant full length Human Tollip.
MW: ~ 33 kDa
Swis Prot.: Q9H0E2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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