TOP3B antibody (clone 4H7), anti-human
€435.00
In stock
SKU
AC-AT4307a
Catalog Number: AC-AT4307a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF
Request Information AC-AT4307a">Request Information
Background:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described.
Other Names:
DNA topoisomerase 3-beta-1, DNA topoisomerase III beta-1, TOP3B, TOP3B1
Antigen Type:
Recombinant Protein
Gene Name: TOP3B
Gene ID: 8940
NCBI Accession: NP_001269041.1;NP_001269042.1;NP_003926.1
Primary Accession: O95985
Other Accession: BC002432
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described.
Other Names:
DNA topoisomerase 3-beta-1, DNA topoisomerase III beta-1, TOP3B, TOP3B1
Antigen Type:
Recombinant Protein
Gene Name: TOP3B
Gene ID: 8940
NCBI Accession: NP_001269041.1;NP_001269042.1;NP_003926.1
Primary Accession: O95985
Other Accession: BC002432
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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