Topoisomerase II alpha (clone TOP2A/1362), anti-human

Background:
It recognizes a 170kDa protein, which is identified as topoisomerase II.  shows no cross-reaction with Topoisomerase II or I. Topo II plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells. Topo II is also implicated in drug resistance of tumor cells.

Other Names:
ATP hydrolyzing DNA topoisomerase II alfa; DNA gyrase; DNA topoisomerase (ATP hydrolyzing); DNA topoisomerase 2 alpha; DNA topoisomerase II 170kD; DNA topoisomerase II alpha; DNA Topoisomerase2; TOP2A; Topoisomerase DNA II alpha 170kDa; TP2A

Antigen Type:
Recombinant protein

Gene Name: TOP2A
Gene ID: 7153
Primary Accession: P11388
Other Accession: 156346