Topoisomerase II alpha TOP2A monoclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO14288
Catalog Number: AC-ABO14288
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Description: Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody . Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity)..
Other Names: DNA topoisomerase 2-alpha, 5.6.2.2 {ECO:0000255|PROSITE-ProRule:PRU00995, ECO:0000269|PubMed:19222228, ECO:0000269|PubMed:19697956}, DNA topoisomerase II, alpha isozyme, TOP2A, TOP2
Clone Name(s):
Clone: FB-20
Subcellular Localization: Cytoplasm. Nucleus, nucleoplasm. Generally located in the nucleoplasm.
Gene ID: 7153
Immunogen: A synthesized peptide derived from human Topoisomerase II alpha
Calculated MW: 174385
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity)..
Other Names: DNA topoisomerase 2-alpha, 5.6.2.2 {ECO:0000255|PROSITE-ProRule:PRU00995, ECO:0000269|PubMed:19222228, ECO:0000269|PubMed:19697956}, DNA topoisomerase II, alpha isozyme, TOP2A, TOP2
Clone Name(s):
Clone: FB-20
Subcellular Localization: Cytoplasm. Nucleus, nucleoplasm. Generally located in the nucleoplasm.
Gene ID: 7153
Immunogen: A synthesized peptide derived from human Topoisomerase II alpha
Calculated MW: 174385
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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