TPMT antibody (clone 1B5), anti-human
€435.00
In stock
SKU
AC-AT4320a
Catalog Number: AC-AT4320a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, IF
Request Information AC-AT4320a">Request Information
Background:
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Other Names:
Thiopurine S-methyltransferase, Thiopurine methyltransferase, TPMT
Antigen Type:
Recombinant Protein
Gene Name: TPMT
Gene ID: 7172
NCBI Accession: NP_000358.1
Primary Accession: P51580
Other Accession: BC005339
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Other Names:
Thiopurine S-methyltransferase, Thiopurine methyltransferase, TPMT
Antigen Type:
Recombinant Protein
Gene Name: TPMT
Gene ID: 7172
NCBI Accession: NP_000358.1
Primary Accession: P51580
Other Accession: BC005339
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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