TRADD antibody (clone 3G1), anti-human
€435.00
In stock
SKU
AC-AT4329a
Catalog Number: AC-AT4329a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF
Request Information AC-AT4329a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF
Request Information AC-AT4329a">Request Information
Background:
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Other Names:
Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, TRADD
Antigen Type:
Recombinant Protein
Gene Name: TRADD {ECO:0000303|PubMed:7758105, ECO:0000312|HGNC:HGNC:12030}
Gene ID: 8717
NCBI Accession: NP_003780.1
Primary Accession: Q15628
Other Accession: NM_003789
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Other Names:
Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, TRADD
Antigen Type:
Recombinant Protein
Gene Name: TRADD {ECO:0000303|PubMed:7758105, ECO:0000312|HGNC:HGNC:12030}
Gene ID: 8717
NCBI Accession: NP_003780.1
Primary Accession: Q15628
Other Accession: NM_003789
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review