TRAF3IP2 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP19044b
Background:
This gene encodes a protein involved in regulatingresponses to cytokines by members of the Rel/NF-kappaBtranscription factor family. These factors play a central role ininnate immunity in response to pathogens, inflammatory signals andstress. This gene product interacts with TRAF proteins (tumornecrosis factor receptor-associated factors) and either I-kappaBkinase or MAP kinase to activate either NF-kappaB or Jun kinase.Several alternative transcripts encoding different isoforms havebeen identified. Another transcript, which does not encode aprotein and is transcribed in the opposite orientation, has beenidentified. Overexpression of this transcript has been shown toreduce expression of at least one of the protein encodingtranscripts, suggesting it has a regulatory role in the expressionof this gene.
Other Names:
Adapter protein CIKS, Connection to IKK and SAPK/JNK, Nuclear factor NF-kappa-B activator 1, ACT1, TRAF3-interacting protein 2, TRAF3IP2, C6orf2, C6orf4, C6orf5, C6orf6
Gene Name: TRAF3IP2 (HGNC:1343)
Gene ID: 10758
Primary Accession: O43734
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a protein involved in regulatingresponses to cytokines by members of the Rel/NF-kappaBtranscription factor family. These factors play a central role ininnate immunity in response to pathogens, inflammatory signals andstress. This gene product interacts with TRAF proteins (tumornecrosis factor receptor-associated factors) and either I-kappaBkinase or MAP kinase to activate either NF-kappaB or Jun kinase.Several alternative transcripts encoding different isoforms havebeen identified. Another transcript, which does not encode aprotein and is transcribed in the opposite orientation, has beenidentified. Overexpression of this transcript has been shown toreduce expression of at least one of the protein encodingtranscripts, suggesting it has a regulatory role in the expressionof this gene.
Other Names:
Adapter protein CIKS, Connection to IKK and SAPK/JNK, Nuclear factor NF-kappa-B activator 1, ACT1, TRAF3-interacting protein 2, TRAF3IP2, C6orf2, C6orf4, C6orf5, C6orf6
Gene Name: TRAF3IP2 (HGNC:1343)
Gene ID: 10758
Primary Accession: O43734
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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