TRAF3IP2 antibody (clone 4A3), anti-human
€435.00
In stock
SKU
AC-AT4330a
Catalog Number: AC-AT4330a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT4330a">Request Information
Background:
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Other Names:
Adapter protein CIKS, Connection to IKK and SAPK/JNK, Nuclear factor NF-kappa-B activator 1, ACT1, TRAF3-interacting protein 2, TRAF3IP2, C6orf2, C6orf4, C6orf5, C6orf6
Antigen Type:
Recombinant Protein
Gene Name: TRAF3IP2 (HGNC:1343)
Gene ID: 10758
NCBI Accession: NP_001157753.1;NP_001157755.1;NP_679211.2
Primary Accession: O43734
Other Accession: BC002823
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Other Names:
Adapter protein CIKS, Connection to IKK and SAPK/JNK, Nuclear factor NF-kappa-B activator 1, ACT1, TRAF3-interacting protein 2, TRAF3IP2, C6orf2, C6orf4, C6orf5, C6orf6
Antigen Type:
Recombinant Protein
Gene Name: TRAF3IP2 (HGNC:1343)
Gene ID: 10758
NCBI Accession: NP_001157753.1;NP_001157755.1;NP_679211.2
Primary Accession: O43734
Other Accession: BC002823
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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