TRAF4 antibody (clone 3F6), anti-human
€435.00
In stock
SKU
AC-AT4331a
Catalog Number: AC-AT4331a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT4331a">Request Information
Background:
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.
Other Names:
TNF receptor-associated factor 4, Cysteine-rich domain associated with RING and Traf domains protein 1, Metastatic lymph node gene 62 protein, MLN 62, RING finger protein 83, TRAF4, CART1, MLN62, RNF83
Antigen Type:
Recombinant Protein
Gene Name: TRAF4
Gene ID: 9618
NCBI Accession: NP_004286.2
Primary Accession: Q9BUZ4
Other Accession: BC001769
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.
Other Names:
TNF receptor-associated factor 4, Cysteine-rich domain associated with RING and Traf domains protein 1, Metastatic lymph node gene 62 protein, MLN 62, RING finger protein 83, TRAF4, CART1, MLN62, RNF83
Antigen Type:
Recombinant Protein
Gene Name: TRAF4
Gene ID: 9618
NCBI Accession: NP_004286.2
Primary Accession: Q9BUZ4
Other Accession: BC001769
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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