TRAF6 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6076
Background:
Tumor necrosis factor receptor-associated factor 6 (TRAF6) regulates adaptive immunity, innate immunity and bone metabolism. TRAF6 is a ubiquitin (Ub) ligase that mediates the activation of protein kinases, such as transforming growth factor beta-activated kinase (TAK1) and IκB kinase (IKK), by catalyzing the formation of a unique polyubiquitin chain linked through Lys 63 of Ub. TRAF6 is essential for activating NFκB signaling pathway in response to interleukin-1 and Toll-like receptor ligands. The coiled-coil domain of TRAF6 is essential for its auto-ubiquitination and activating NFκB signaling pathway.
Alternative Name:
E3 ubiquitin-protein ligase TRAF6, Interleukin 1 signal transducer, Interleukin-1 signal transducer, MGC 3310, MGC 3310, MGC:3310, MGC3310, OTTHUMP00000232772, OTTHUMP00000232773, RING finger protein 85, RNF 85, RNF85, RNF85, TNF receptor associated factor 6, TNF receptor associated factor 6, TNF receptor-associated factor 6, TRAF 6, Traf6, TRAF6,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: TRAF6 polyclonal antibody detects endogenous levels of TRAF6 protein.
Immunogen:
Recombinant full length Human TRAF6.
MW: ~ 58 kDa
Swis Prot.: Q9Y4K3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Tumor necrosis factor receptor-associated factor 6 (TRAF6) regulates adaptive immunity, innate immunity and bone metabolism. TRAF6 is a ubiquitin (Ub) ligase that mediates the activation of protein kinases, such as transforming growth factor beta-activated kinase (TAK1) and IκB kinase (IKK), by catalyzing the formation of a unique polyubiquitin chain linked through Lys 63 of Ub. TRAF6 is essential for activating NFκB signaling pathway in response to interleukin-1 and Toll-like receptor ligands. The coiled-coil domain of TRAF6 is essential for its auto-ubiquitination and activating NFκB signaling pathway.
Alternative Name:
E3 ubiquitin-protein ligase TRAF6, Interleukin 1 signal transducer, Interleukin-1 signal transducer, MGC 3310, MGC 3310, MGC:3310, MGC3310, OTTHUMP00000232772, OTTHUMP00000232773, RING finger protein 85, RNF 85, RNF85, RNF85, TNF receptor associated factor 6, TNF receptor associated factor 6, TNF receptor-associated factor 6, TRAF 6, Traf6, TRAF6,
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: TRAF6 polyclonal antibody detects endogenous levels of TRAF6 protein.
Immunogen:
Recombinant full length Human TRAF6.
MW: ~ 58 kDa
Swis Prot.: Q9Y4K3
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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