TRAIL-R2 Functional mAb (clone HS201) preservative free, anti-human
€455.00
In stock
SKU
AC-ADP0013-U0100
Catalog Number: AC-ADP0013-U0100
Size: 100 µg
Isotype: Mouse IgG1
Applications: IHC-P, FC, ICC, IP
Datasheet
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Size: 100 µg
Isotype: Mouse IgG1
Applications: IHC-P, FC, ICC, IP
Datasheet
Request Information
Background:
TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa.
Other Names:
TRAIL Receptor 2; DR5; KILLER; TNFRSF10B; CD262
Gene Name: TNFRSF10B
Gene ID: 8795
Primary Accession: O14763
TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa.
Other Names:
TRAIL Receptor 2; DR5; KILLER; TNFRSF10B; CD262
Gene Name: TNFRSF10B
Gene ID: 8795
Primary Accession: O14763
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