Transglutaminase II [clone TGM2/419], anti-human, monkey, rabbit, mouse, rat

Description: Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healingLocalization: membrane, cytoplasmDilution: 50-200Positive Control: breast caHIER: citrate pH6.0 or EDTA pH8.0Status: RUO