Contactin 1 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73305
Catalog Number: AC-AP60590
Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC, IHC
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC, IHC
Datasheet
Request Information
Background:
Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).
Other Names:
CNTN1; Contactin-1; Glycoprotein gp135; Neural cell surface protein F3
Antigen Type: synthetic peptide
Antigen Type: CNTN1
Gene ID: 1272
Primary Accession: Q12860
Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).
Other Names:
CNTN1; Contactin-1; Glycoprotein gp135; Neural cell surface protein F3
Antigen Type: synthetic peptide
Antigen Type: CNTN1
Gene ID: 1272
Primary Accession: Q12860
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