PRC1 polyclonal, anti-human
€470.00
In stock
SKU
AC-AP74081
Catalog Number: AC-AP61359
Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IF/IC
Datasheet
Request Information
Background:
Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).
Other Names:
Protein regulator of cytokinesis 1
Antigen Type: synthetic peptide
Antigen Type: PRC1 (HGNC:9341)
Gene ID: 9055
Primary Accession: O43663
Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).
Other Names:
Protein regulator of cytokinesis 1
Antigen Type: synthetic peptide
Antigen Type: PRC1 (HGNC:9341)
Gene ID: 9055
Primary Accession: O43663
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