TRIM21 polyclonal, anti-human, mouse, rat

TRIM21 polyclonal, anti-human, mouse, rat

€388.00
In stock
SKU
BS7333
Catalog Number: BS7333
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, IHC, IF

Datasheet
Background:
TRIM21 has multiple N-terminal zinc finger motifs(has E3 ligase activity), a central leucine zipper, and a potential N-glycosylation site. TRIM3 is a E3 ubiquitin-protein ligase. It can form a ubiquitin ligase complex with E2 UBE2D2, which function not only for the uniquitination of USP4 and IKBKB but also for its self-ubiquitination. It has a role in the regulation of the cell cycle progression and could enhance the decapping activity of DCP2. It can exist in all mammalian cells as a ribonucleoprotein particle , which composed of a single polypeptide and 1 of 4 small RNA molecules.

Alternative Name:
52 kDa ribonucleoprotein autoantigen Ro/SS-A, 52 kDa Ro protein, 52kD Ro/SSA autoantigen, Autoantigen Ro/SSA, 52-KD, E3 ubiquitin-protein ligase TRIM21, RING finger protein 81, RNF81, Ro 52, Ro(SS-A), Ro52, RO52_HUMAN, Sicca syndrome antigen A, Sjoegren syndrome type A antigen, Sjogren syndrome antigen A1, Sjogren syndrome type A antigen, SS-A, SSA, SSA1: Sjogren syndrome antigen A1 (52kDa ribonucleoprotein autoantigen SS-A/Ro), TRIM21, Tripartite motif protein TRIM21, Tripartite motif-containing 21, Tripartite motif-containing protein 21,

Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Specificity: TRIM21 polyclonal antibody detects endogenous levels of TRIM21 protein.

Immunogen:
Recombinant full length Human TRIM21.

MW: ~54 kDa

Swis Prot.: P19474

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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