TRIM25 antibody (clone 5C3), anti-human
€435.00
In stock
SKU
AC-AT4347a
Catalog Number: AC-AT4347a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF
Request Information AC-AT4347a">Request Information
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Other Names:
E3 ubiquitin/ISG15 ligase TRIM25, 632n3, Estrogen-responsive finger protein, RING finger protein 147, Tripartite motif-containing protein 25, Ubiquitin/ISG15-conjugating enzyme TRIM25, Zinc finger protein 147, TRIM25, EFP, RNF147, ZNF147
Antigen Type:
Recombinant Protein
Gene Name: TRIM25
Gene ID: 7706
NCBI Accession: NP_005073.2
Primary Accession: Q14258
Other Accession: NM_005082
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Other Names:
E3 ubiquitin/ISG15 ligase TRIM25, 632n3, Estrogen-responsive finger protein, RING finger protein 147, Tripartite motif-containing protein 25, Ubiquitin/ISG15-conjugating enzyme TRIM25, Zinc finger protein 147, TRIM25, EFP, RNF147, ZNF147
Antigen Type:
Recombinant Protein
Gene Name: TRIM25
Gene ID: 7706
NCBI Accession: NP_005073.2
Primary Accession: Q14258
Other Accession: NM_005082
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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