TRIM3 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13286a
Background:
The protein encoded by this gene is a member of thetripartite motif (TRIM) family, also called the'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins.The TRIM motif includes three zinc-binding domains, a RING, a B-boxtype 1 and a B-box type 2, and a coiled-coil region. This proteinlocalizes to cytoplasmic filaments. It is similar to a rat proteinwhich is a specific partner for the tail domain of myosin V, aclass of myosins which are involved in the targeted transport oforganelles. The rat protein can also interact with alpha-actinin-4.Thus it is suggested that this human protein may play a role inmyosin V-mediated cargo transport. Alternatively spliced transcriptvariants encoding the same isoform have been identified. [providedby RefSeq].
Other Names:
Tripartite motif-containing protein 3, Brain-expressed RING finger protein, RING finger protein 22, RING finger protein 97, TRIM3, BERP, RNF22, RNF97
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13286a was selected from the N-term region of TRIM3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TRIM3
Gene ID: 10612
Primary Accession: O75382
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of thetripartite motif (TRIM) family, also called the'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins.The TRIM motif includes three zinc-binding domains, a RING, a B-boxtype 1 and a B-box type 2, and a coiled-coil region. This proteinlocalizes to cytoplasmic filaments. It is similar to a rat proteinwhich is a specific partner for the tail domain of myosin V, aclass of myosins which are involved in the targeted transport oforganelles. The rat protein can also interact with alpha-actinin-4.Thus it is suggested that this human protein may play a role inmyosin V-mediated cargo transport. Alternatively spliced transcriptvariants encoding the same isoform have been identified. [providedby RefSeq].
Other Names:
Tripartite motif-containing protein 3, Brain-expressed RING finger protein, RING finger protein 22, RING finger protein 97, TRIM3, BERP, RNF22, RNF97
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13286a was selected from the N-term region of TRIM3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TRIM3
Gene ID: 10612
Primary Accession: O75382
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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