TRIM5 antibody (clone 2A6), anti-human
€435.00
In stock
SKU
AC-AT4358a
Catalog Number: AC-AT4358a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E
Request Information AC-AT4358a">Request Information
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Other Names:
Tripartite motif-containing protein 5, 632-, RING finger protein 88, TRIM5, RNF88
Antigen Type:
Recombinant Protein
Gene Name: TRIM5
Gene ID: 85363
NCBI Accession: NP_149023.2;NP_149083.2;NP_149084.2
Primary Accession: Q9C035
Other Accession: NM_033034
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Other Names:
Tripartite motif-containing protein 5, 632-, RING finger protein 88, TRIM5, RNF88
Antigen Type:
Recombinant Protein
Gene Name: TRIM5
Gene ID: 85363
NCBI Accession: NP_149023.2;NP_149083.2;NP_149084.2
Primary Accession: Q9C035
Other Accession: NM_033034
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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