TRIM63 antibody (clone 6G6), anti-human
€435.00
In stock
SKU
AC-AT4361a
Catalog Number: AC-AT4361a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT4361a">Request Information
Background:
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.
Other Names:
E3 ubiquitin-protein ligase TRIM63, 632-, Iris RING finger protein, Muscle-specific RING finger protein 1, MuRF-1, MuRF1, RING finger protein 28, Striated muscle RING zinc finger protein, Tripartite motif-containing protein 63, TRIM63, IRF, MURF1, RNF28, SMRZ
Antigen Type:
Recombinant Protein
Gene Name: TRIM63
Gene ID: 84676
NCBI Accession: NP_115977.2
Primary Accession: Q969Q1
Other Accession: NM_032588
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.
Other Names:
E3 ubiquitin-protein ligase TRIM63, 632-, Iris RING finger protein, Muscle-specific RING finger protein 1, MuRF-1, MuRF1, RING finger protein 28, Striated muscle RING zinc finger protein, Tripartite motif-containing protein 63, TRIM63, IRF, MURF1, RNF28, SMRZ
Antigen Type:
Recombinant Protein
Gene Name: TRIM63
Gene ID: 84676
NCBI Accession: NP_115977.2
Primary Accession: Q969Q1
Other Accession: NM_032588
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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