Tropomyosin(36/39 kDa) (clone TM31), anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO10479
Catalog Number: AC-ABO10479
Size: 100 µg
Isotype: Mouse IgG
Applications: WB
Datasheet
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Size: 100 µg
Isotype: Mouse IgG
Applications: WB
Datasheet
Request Information
Description: Mouse IgG monoclonal antibody for Tropomyosin (36/39 kDa), tropomyosin 1 (alpha) (TPM1) detection. Tested with WB in Human;mouse;rat;chicken. No cross reactivity with other proteins.Protein Name: Tropomyosin alpha-1 chain
Protein Function:
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Other Names: Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1, Tpm1, Alpha-tm, Tpma
Clone Name(s):
TM31
Subcellular Localization: Cytoplasm, cytoskeleton.
Tissue Specificity: TPM1: Detected in primary breast cancer tissues butundetectable in normal breast tissues in Sudanese patients.Isoform 1 is expressed in adult and fetal skeletal muscle andcardiac tissues, with higher expression levels in the cardiactissues. Isoform 10 is expressed in adult and fetal cardiactissues, but not in skeletal muscle.
Gene ID: 24851
Immunogen: Chicken gizzard tropomyosin.
Calculated MW: 32681
Purification: Ascites
Format: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Concentration (mg/ml): Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Function:
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Other Names: Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1, Tpm1, Alpha-tm, Tpma
Clone Name(s):
TM31
Subcellular Localization: Cytoplasm, cytoskeleton.
Tissue Specificity: TPM1: Detected in primary breast cancer tissues butundetectable in normal breast tissues in Sudanese patients.Isoform 1 is expressed in adult and fetal skeletal muscle andcardiac tissues, with higher expression levels in the cardiactissues. Isoform 10 is expressed in adult and fetal cardiactissues, but not in skeletal muscle.
Gene ID: 24851
Immunogen: Chicken gizzard tropomyosin.
Calculated MW: 32681
Purification: Ascites
Format: Lyophilized
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Contents: Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Concentration (mg/ml): Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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