Troponin I-C (phospho Ser43) Polyclonal Antibody

Troponin I-C (phospho Ser43) Polyclonal Antibody

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SKU
ELK-ES7406
Catalog Number: ELK-ES7406
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
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Background:
troponin I3, cardiac type(TNNI3) Homo sapiens Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008],

Alternative Names:
TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I

Immunogen: The antiserum was produced against synthesized peptide derived from human TNNI3 around the phosphorylation site of Ser43. AA range:11-60

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 26

GeneID: TNNI3

Storage: -20°C/1 year

NOTE: For Research Use Only
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