TRPC5 polyclonal, anti-human
€388.00
In stock
SKU
BS70974
Background:
Human TRP1 protein is a 793 amino acid cation channel that is expressed in fetal and adult brain and in adult heart, testis and ovary, where it may influence store-operated Ca2+ entry as a component of capacitative calcium entry (CCE) complexes. The brain-specific subunit TRP5 forms a nonselective cation channel with TRP1 in the hippocampus that is activated by Gq-coupled receptors, but not by depletion of intracellular Ca2+ stores. The gene encoding human TRP5 maps to chromosome Xp23, which also contains loci for nonsyndromic mental retardation and X-linked disorders.
Alternative Name:
Short transient receptor potential channel 5, TrpC5, Transient receptor protein 5, TRP-5, hTRP-5, hTRP5, TRPC5, TRP5
Application Dilution: WB: 1:500 - 1:2000
Specificity: TRPC5 polyclonal antibody detects endogenous levels of TRPC5 protein.
Immunogen:
Recombinant protein of human TRPC5.
MW: ~ 111 kDa
Swis Prot.: Q9UL62
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Human TRP1 protein is a 793 amino acid cation channel that is expressed in fetal and adult brain and in adult heart, testis and ovary, where it may influence store-operated Ca2+ entry as a component of capacitative calcium entry (CCE) complexes. The brain-specific subunit TRP5 forms a nonselective cation channel with TRP1 in the hippocampus that is activated by Gq-coupled receptors, but not by depletion of intracellular Ca2+ stores. The gene encoding human TRP5 maps to chromosome Xp23, which also contains loci for nonsyndromic mental retardation and X-linked disorders.
Alternative Name:
Short transient receptor potential channel 5, TrpC5, Transient receptor protein 5, TRP-5, hTRP-5, hTRP5, TRPC5, TRP5
Application Dilution: WB: 1:500 - 1:2000
Specificity: TRPC5 polyclonal antibody detects endogenous levels of TRPC5 protein.
Immunogen:
Recombinant protein of human TRPC5.
MW: ~ 111 kDa
Swis Prot.: Q9UL62
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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