TRPM2 polyclonal, anti-human
€388.00
In stock
SKU
BS7930
Background:
Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
Alternative Name:
EREG 1, EREG1, Estrogen responsive element associated gene 1, Estrogen responsive element associated gene 1 protein, Estrogen-responsive element-associated gene 1 protein, KNP 3, KNP3, Long transient receptor potential channel 2, LTRPC 2, LTrpC-2, LTRPC2, MGC133383, NUDT9H, NUDT9L1, putative Ca2+ channel protein, transient receptor potential cation channel subfamily M member 2, Transient receptor potential channel 7, TRPC 7, TRPC7, TRPM 2, Trpm2, TRPM2_HUMAN,
Application Dilution: IF: 1:50 - 1:100
Specificity: TRPM2 polyclonal antibody detects endogenous levels of TRPM2 protein.
Immunogen:
Recombinant full length Human TRPM2.
MW: ~ 171 kDa
Swis Prot.: O94759
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
Alternative Name:
EREG 1, EREG1, Estrogen responsive element associated gene 1, Estrogen responsive element associated gene 1 protein, Estrogen-responsive element-associated gene 1 protein, KNP 3, KNP3, Long transient receptor potential channel 2, LTRPC 2, LTrpC-2, LTRPC2, MGC133383, NUDT9H, NUDT9L1, putative Ca2+ channel protein, transient receptor potential cation channel subfamily M member 2, Transient receptor potential channel 7, TRPC 7, TRPC7, TRPM 2, Trpm2, TRPM2_HUMAN,
Application Dilution: IF: 1:50 - 1:100
Specificity: TRPM2 polyclonal antibody detects endogenous levels of TRPM2 protein.
Immunogen:
Recombinant full length Human TRPM2.
MW: ~ 171 kDa
Swis Prot.: O94759
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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