TRPM8 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60452
Background:
TRPM8 (transient receptor potential cation channel, subfamily M, member 8), also known as TRPP8 or LTRPC6, is a 1,104 amino acid multi-pass membrane protein that belongs to the TRP family of regulatory channel proteins. Expressed at high levels in prostate, TRPM8 functions as a receptor-activated cation channel that is permeable to monovalent cations (such as sodium and potassium) and divalent Ca2+ and is involved in the detection of temperature sensations (such as the feeling of coolness) throughout the body. TRPM8 is overexpressed in prostate tumors, as well as in colon, breast and lung cancers, suggesting an important role for TRPM8 in tumorigenesis.
Alternative Name:
Transient receptor potential cation channel subfamily M member 8, Long transient receptor potential channel 6, LTrpC-6, LTrpC6, Transient receptor potential p8, Trp-p8, LTRPC6, TRPP8
Application Dilution: WB: 1:500~1:1000
Specificity: TRPM8 polyclonal antibody detects endogenous levels of TRPM8 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TRPM8.
MW: ~ 130 kDa
Swis Prot.: Q7Z2W7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
TRPM8 (transient receptor potential cation channel, subfamily M, member 8), also known as TRPP8 or LTRPC6, is a 1,104 amino acid multi-pass membrane protein that belongs to the TRP family of regulatory channel proteins. Expressed at high levels in prostate, TRPM8 functions as a receptor-activated cation channel that is permeable to monovalent cations (such as sodium and potassium) and divalent Ca2+ and is involved in the detection of temperature sensations (such as the feeling of coolness) throughout the body. TRPM8 is overexpressed in prostate tumors, as well as in colon, breast and lung cancers, suggesting an important role for TRPM8 in tumorigenesis.
Alternative Name:
Transient receptor potential cation channel subfamily M member 8, Long transient receptor potential channel 6, LTrpC-6, LTrpC6, Transient receptor potential p8, Trp-p8, LTRPC6, TRPP8
Application Dilution: WB: 1:500~1:1000
Specificity: TRPM8 polyclonal antibody detects endogenous levels of TRPM8 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TRPM8.
MW: ~ 130 kDa
Swis Prot.: Q7Z2W7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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