TRPV1 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13988a
Background:
Capsaicin, the main pungent ingredient in hot chilipeppers, elicits a sensation of burning pain by selectivelyactivating sensory neurons that convey information about noxiousstimuli to the central nervous system. The protein encoded by thisgene is a receptor for capsaicin and is a non-selective cationchannel that is structurally related to members of the TRP familyof ion channels. This receptor is also activated by increases intemperature in the noxious range, suggesting that it functions as atransducer of painful thermal stimuli in vivo. Four transcriptvariants encoding the same protein, but with different 5' UTRsequence, have been described for this gene.
Other Names:
Transient receptor potential cation channel subfamily V member 1, TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, TRPV1, VR1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13988a was selected from the N-term region of TRPV1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TRPV1
Gene ID: 7442
Primary Accession: Q8NER1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Capsaicin, the main pungent ingredient in hot chilipeppers, elicits a sensation of burning pain by selectivelyactivating sensory neurons that convey information about noxiousstimuli to the central nervous system. The protein encoded by thisgene is a receptor for capsaicin and is a non-selective cationchannel that is structurally related to members of the TRP familyof ion channels. This receptor is also activated by increases intemperature in the noxious range, suggesting that it functions as atransducer of painful thermal stimuli in vivo. Four transcriptvariants encoding the same protein, but with different 5' UTRsequence, have been described for this gene.
Other Names:
Transient receptor potential cation channel subfamily V member 1, TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, TRPV1, VR1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13988a was selected from the N-term region of TRPV1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: TRPV1
Gene ID: 7442
Primary Accession: Q8NER1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review