TSC1 Blocking Peptide (Center T417)
€363.00
In stock
SKU
AC-BP20328c
Background:
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
Other Names:
Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC
Gene Name: TSC1 {ECO:0000303|PubMed:9242607, ECO:0000312|HGNC:HGNC:12362}
Gene ID: 7248
Primary Accession: Q92574
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
Other Names:
Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC
Gene Name: TSC1 {ECO:0000303|PubMed:9242607, ECO:0000312|HGNC:HGNC:12362}
Gene ID: 7248
Primary Accession: Q92574
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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