TSEN2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative Name:
SEN2, PCH2B, SEN2L,

Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:100

Specificity: TSEN2 polyclonal antibody detects endogenous levels of TSEN2 protein.

Immunogen:
Recombinant protein of human TSEN2.

MW: ~ 53 kDa

Swis Prot.: Q8NCE0

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.