TSHZ1 polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS61054
Background:
The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.
Alternative Name:
Teashirt homolog 1, Antigen NY-CO-33, Serologically defined colon cancer antigen 33, TSHZ1, SDCCAG33, TSH1
Application Dilution: WB: 1:500~1:1000
Specificity: TSHZ1 polyclonal antibody detects endogenous levels of TSHZ1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TSHZ1.
MW: ~ 113 kDa
Swis Prot.: Q6ZSZ6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. TSHZ1 has been found to be required for axial skeleton, soft palate and middle ear development in mice and may be involved in a common pathway with the Hox genes. Both TSHZ1 and the related protein TSHZ3 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4.
Alternative Name:
Teashirt homolog 1, Antigen NY-CO-33, Serologically defined colon cancer antigen 33, TSHZ1, SDCCAG33, TSH1
Application Dilution: WB: 1:500~1:1000
Specificity: TSHZ1 polyclonal antibody detects endogenous levels of TSHZ1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TSHZ1.
MW: ~ 113 kDa
Swis Prot.: Q6ZSZ6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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