TSSK6 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61496
Background:
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
Alternative Name:
Testis-specific serine/threonine-protein kinase 6, TSK-6, TSSK-6, Testis-specific kinase 6, Cancer/testis antigen 72, CT72, Serine/threonine-protein kinase SSTK, Small serine/threonine kinase, TSSK6, FKSG82
Application Dilution: WB: 1:500~1:1000
Specificity: TSSK6 polyclonal antibody detects endogenous levels of TSSK6 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 110-155 of Human TSSK6A.
MW: ~ 30 kDa
Swis Prot.: Q9BXA6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
Alternative Name:
Testis-specific serine/threonine-protein kinase 6, TSK-6, TSSK-6, Testis-specific kinase 6, Cancer/testis antigen 72, CT72, Serine/threonine-protein kinase SSTK, Small serine/threonine kinase, TSSK6, FKSG82
Application Dilution: WB: 1:500~1:1000
Specificity: TSSK6 polyclonal antibody detects endogenous levels of TSSK6 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 110-155 of Human TSSK6A.
MW: ~ 30 kDa
Swis Prot.: Q9BXA6
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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