TTF1/NKX2.1 [clone SP141], anti-human

Description: Anti-TTF-1 (Thyroid Transcription Factor 1) is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 labelling is also seen in thyroid malignancies.Localization: nucleusDilution: 25-100Positive Control: lung adenoca, thyroid caHIER: citrate PH6.0 or EDTA pH8.0Status: RUO