TTK antibody (clone 4G9), anti-human
€435.00
In stock
SKU
AC-AT4391a
Catalog Number: AC-AT4391a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT4391a">Request Information
Background:
This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
Other Names:
Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYT, TTK, MPS1, MPS1L1
Antigen Type:
Recombinant Protein
Gene Name: TTK
Gene ID: 7272
NCBI Accession: NP_001160163.1;NP_003309.2
Primary Accession: P33981
Other Accession: BC000633
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.
Other Names:
Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYT, TTK, MPS1, MPS1L1
Antigen Type:
Recombinant Protein
Gene Name: TTK
Gene ID: 7272
NCBI Accession: NP_001160163.1;NP_003309.2
Primary Accession: P33981
Other Accession: BC000633
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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