TTLL12 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71116
Background:
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
Alternative Name:
KIAA0153, Tubulin--tyrosine ligase-like protein 12
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: TTLL12 polyclonal antibody detects endogenous levels of TTLL12 protein.
Immunogen:
Recombinant protein of human TTLL12.
MW: ~ 74 kDa
Swis Prot.: Q14166
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
Alternative Name:
KIAA0153, Tubulin--tyrosine ligase-like protein 12
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: TTLL12 polyclonal antibody detects endogenous levels of TTLL12 protein.
Immunogen:
Recombinant protein of human TTLL12.
MW: ~ 74 kDa
Swis Prot.: Q14166
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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