TTR polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7273
Background:
Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).
Alternative Name:
Amyloid polyneuropathy, Amyloidosis I, ATTR, Carpal tunnel syndrome 1, CTS, CTS1, Dysprealbuminemic euthyroidal hyperthyroxinemia, Dystransthyretinemic hyperthyroxinemia, HsT2651, PALB, Prealbumin amyloidosis type I, Prealbumin, Senile systemic amyloidosis, TBPA, Thyroxine binding prealbumin, Transthyretin, TTHY_HUMAN, TTR, TTR protein,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: TTR polyclonal antibody detects endogenous levels of TTR protein.
Immunogen:
Recombinant full length Human TTR.
MW: ~ 16 kDa
Swis Prot.: P02766
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermed-iate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).
Alternative Name:
Amyloid polyneuropathy, Amyloidosis I, ATTR, Carpal tunnel syndrome 1, CTS, CTS1, Dysprealbuminemic euthyroidal hyperthyroxinemia, Dystransthyretinemic hyperthyroxinemia, HsT2651, PALB, Prealbumin amyloidosis type I, Prealbumin, Senile systemic amyloidosis, TBPA, Thyroxine binding prealbumin, Transthyretin, TTHY_HUMAN, TTR, TTR protein,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: TTR polyclonal antibody detects endogenous levels of TTR protein.
Immunogen:
Recombinant full length Human TTR.
MW: ~ 16 kDa
Swis Prot.: P02766
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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