TUBA3C/TUBA3D/TUBA3E polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61748
Background:
Tubulin is a major cytoskeleton component that has five distinct forms, designated α, β, γ, δ and ε Tubulin. α and β tubulins form heterodimers which multimerize to form a microtubule filament. There are 5 β Tubulin isoforms (β1, β2, β3, β4A and β4B) that are expressed in mammalian tissues. β1 and β4 are present throughout the cytosol, β2 is present in the nuclei and nucleoplasm, and β3 is a neuron-specific cytoskeletal protein. γ Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both δ Tubulin and ε Tubulin are associated with the centrosome. δ Tubulin is a homolog of the Chlamydomonas δ Tubulin Uni3 and is found in association with the centrioles, whereas ε Tubulin localizes to the pericentriolar material. ε Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.
Alternative Name:
Tubulin alpha-3C/D chain, Alpha-tubulin 2, Alpha-tubulin 3C/D, Tubulin alpha-2 chain, Detyrosinated tubulin alpha-3C/D chain, TUBA3C, TUBA2, TUBA3D, Tubulin alpha-3E chain, Alpha-tubulin 3E, Detyrosinated tubulin alpha-3E chain, TUBA3E
Application Dilution: WB: 1:500~1:1000
Specificity: TUBA3C/TUBA3D/TUBA3E polyclonal antibody detects endogenous levels of TUBA3C/TUBA3D/TUBA3E protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 400-450 of Human TUBA3C.
MW: ~ 55 kDa
Swis Prot.: Q13748/Q6PEY2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.4.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Tubulin is a major cytoskeleton component that has five distinct forms, designated α, β, γ, δ and ε Tubulin. α and β tubulins form heterodimers which multimerize to form a microtubule filament. There are 5 β Tubulin isoforms (β1, β2, β3, β4A and β4B) that are expressed in mammalian tissues. β1 and β4 are present throughout the cytosol, β2 is present in the nuclei and nucleoplasm, and β3 is a neuron-specific cytoskeletal protein. γ Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both δ Tubulin and ε Tubulin are associated with the centrosome. δ Tubulin is a homolog of the Chlamydomonas δ Tubulin Uni3 and is found in association with the centrioles, whereas ε Tubulin localizes to the pericentriolar material. ε Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.
Alternative Name:
Tubulin alpha-3C/D chain, Alpha-tubulin 2, Alpha-tubulin 3C/D, Tubulin alpha-2 chain, Detyrosinated tubulin alpha-3C/D chain, TUBA3C, TUBA2, TUBA3D, Tubulin alpha-3E chain, Alpha-tubulin 3E, Detyrosinated tubulin alpha-3E chain, TUBA3E
Application Dilution: WB: 1:500~1:1000
Specificity: TUBA3C/TUBA3D/TUBA3E polyclonal antibody detects endogenous levels of TUBA3C/TUBA3D/TUBA3E protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 400-450 of Human TUBA3C.
MW: ~ 55 kDa
Swis Prot.: Q13748/Q6PEY2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.4.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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