Tubulin-alpha (clone Tub-1), anti-human, rat

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Cell Communication, Infectious Diseases

Description:
Alpha-tubulin ubiquitous (tubulin-alpha) is the major constituent of microtubules. Tubulin-alpha binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Acetylation of tubulin-alpha at Lys-40 stabilizes microtubules and affects affinity and processivity of microtubule motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle progression or cell differentiation to intracellular trafficking and signaling.

Alternate Names: Tubulin alpha, TUBA1, Tubulin-alpha

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P68363

Antigen: Microtubules from chicken embryo brain.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.