Tubulin γ polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71930
Background:
TUB4, the gene for Saccharomyces cerevisiae γ-Tubulin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. γ Tubulin, an essential protein for cell growth, organizes microtubule arrays in the nucleus and cytoplasm. γ Tubulin-depleted cells fail to form functional spindles and arrest during nuclear division. γ Tubulin associates with spindle body components Spc97 and Spc98 to form the γ Tubulin complex. The budding yeast γ Tubulin complex contains one molecule each of Spc97 and Spc98 and two molecules of γ Tubulin. In the SPB, Spc110 binds Spc97 and Spc98 of the γ Tubulin complex. 2D gel analysis indicates five isoforms of γ Tubulin. The phosphorylation of γ Tubulin at Tyr 445 plays a regulatory role in microtubule formation. The incidence rate for this phosphorylation event peaks during G1.
Alternative Name:
Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1, GCP-1, TUBG1, TUBG, Tubulin γ1, Tubulin-γ1, Tubulinγ1
Application Dilution: WB: 1:500 - 1:2000
Specificity: Tubulin γ polyclonal antibody detects endogenous levels of Tubulin γ protein.
Immunogen:
Recombinant protein of human TUBG1
MW: 51kDa
Swis Prot.: P23258
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
TUB4, the gene for Saccharomyces cerevisiae γ-Tubulin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. γ Tubulin, an essential protein for cell growth, organizes microtubule arrays in the nucleus and cytoplasm. γ Tubulin-depleted cells fail to form functional spindles and arrest during nuclear division. γ Tubulin associates with spindle body components Spc97 and Spc98 to form the γ Tubulin complex. The budding yeast γ Tubulin complex contains one molecule each of Spc97 and Spc98 and two molecules of γ Tubulin. In the SPB, Spc110 binds Spc97 and Spc98 of the γ Tubulin complex. 2D gel analysis indicates five isoforms of γ Tubulin. The phosphorylation of γ Tubulin at Tyr 445 plays a regulatory role in microtubule formation. The incidence rate for this phosphorylation event peaks during G1.
Alternative Name:
Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1, GCP-1, TUBG1, TUBG, Tubulin γ1, Tubulin-γ1, Tubulinγ1
Application Dilution: WB: 1:500 - 1:2000
Specificity: Tubulin γ polyclonal antibody detects endogenous levels of Tubulin γ protein.
Immunogen:
Recombinant protein of human TUBG1
MW: 51kDa
Swis Prot.: P23258
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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