TUG (Mouse) (clone 4A11A6G11), anti-mouse
€421.00
In stock
SKU
252636
Protein Family: Chaperones and Folding Catalysts
Pathway and Disease: Cancers
Description:
TUG (Tether containing UBX domain for GLUT4) protein contains a UBX domain for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes and is not mobilized to the plasma membrane by insulin.
Alternate Names: Tether containing UBX domain for GLUT4, Alveolar soft part sarcoma chromosomal region candidate gene 1 protein, Alveolar soft part sarcoma locus, Renal papillary cell carcinoma protein 17, UBX domain-containing protein 9, ASPL, RCC17, TUG, UBXD9, UBXN9, ASPSCR1
Application Notes: WB: 1:500-1:2000
Accession No.: Q9BZE9
Antigen: Purified recombinant fragment of TUG expressed in E. coli.
Format: Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers
Description:
TUG (Tether containing UBX domain for GLUT4) protein contains a UBX domain for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes and is not mobilized to the plasma membrane by insulin.
Alternate Names: Tether containing UBX domain for GLUT4, Alveolar soft part sarcoma chromosomal region candidate gene 1 protein, Alveolar soft part sarcoma locus, Renal papillary cell carcinoma protein 17, UBX domain-containing protein 9, ASPL, RCC17, TUG, UBXD9, UBXN9, ASPSCR1
Application Notes: WB: 1:500-1:2000
Accession No.: Q9BZE9
Antigen: Purified recombinant fragment of TUG expressed in E. coli.
Format: Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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