Tumor Necrosis Factor alpha (TNF-alpha) (clone TNF-E7) biotin, anti-human
€224.00
In stock
SKU
ARP-06-1048-3
Catalog Number: 06-1048-3
Size: 50 µg
Isotype: Mouse IgM
Size: 50 µg
Isotype: Mouse IgM
Background:
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Decription:
Mouse monoclonal Antibody to human TNF alpha, Biotin conjugate
Synonyms: DIF, TNF-alpha, TNFA, TNFSF2
Clone: TNF-E7
Isotype: Mouse IgM
Immunogen: Recombinant human TNF alpha
Reactivity: human
Specificity: Human TNF alpha, does not react with mouse TNF alpha
Form: Affinity Purified, in PBS containing 0.1% Sodium Azide
Applications: ELISA, Immunoblotting
Working Dilution: Direct ELISA: 1:10,000, Western Blot: 1:2000
Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Decription:
Mouse monoclonal Antibody to human TNF alpha, Biotin conjugate
Synonyms: DIF, TNF-alpha, TNFA, TNFSF2
Clone: TNF-E7
Isotype: Mouse IgM
Immunogen: Recombinant human TNF alpha
Reactivity: human
Specificity: Human TNF alpha, does not react with mouse TNF alpha
Form: Affinity Purified, in PBS containing 0.1% Sodium Azide
Applications: ELISA, Immunoblotting
Working Dilution: Direct ELISA: 1:10,000, Western Blot: 1:2000
Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles
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