TXNL1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8129
Background:
Thioredoxins are small redox active proteins that play a variety of roles throughout the cell. TXNL1 (Thioredoxin-like protein 1), also known as TRP32, TXL or TXL-1, is a 289 amino acid cytoplasmic protein that is thought to participate in endocytotic signaling pathways and may act as a redox sensor. Expressed throughout the body, TXNL1 functions to couple oxidative stress to endocytosis, thereby regulating the GDI:Rad5-mediated endocytic response. Additionally, overexpression of TXNL1 inhibits cell proliferation by predisposing the cell to G0/G1 arrest, suggesting that TXNL1 also functions as a transcriptional repressor. TXNL1 shares 99% homology with its mouse homolog and contains one thioredoxin domain.
Alternative Name:
Thioredoxin-like protein 1, 32 kDa thioredoxin-related protein, TXNL1, TRP32, TXL, TXNL
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
Specificity: TXNL1 polyclonal antibody detects endogenous levels of TXNL1 protein.
Immunogen:
Recombinant TXNL1 protein, corresponding to amino acids 1-289 of Human LGR5.
MW: ~ 32 kDa
Swis Prot.: O43396
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Thioredoxins are small redox active proteins that play a variety of roles throughout the cell. TXNL1 (Thioredoxin-like protein 1), also known as TRP32, TXL or TXL-1, is a 289 amino acid cytoplasmic protein that is thought to participate in endocytotic signaling pathways and may act as a redox sensor. Expressed throughout the body, TXNL1 functions to couple oxidative stress to endocytosis, thereby regulating the GDI:Rad5-mediated endocytic response. Additionally, overexpression of TXNL1 inhibits cell proliferation by predisposing the cell to G0/G1 arrest, suggesting that TXNL1 also functions as a transcriptional repressor. TXNL1 shares 99% homology with its mouse homolog and contains one thioredoxin domain.
Alternative Name:
Thioredoxin-like protein 1, 32 kDa thioredoxin-related protein, TXNL1, TRP32, TXL, TXNL
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
Specificity: TXNL1 polyclonal antibody detects endogenous levels of TXNL1 protein.
Immunogen:
Recombinant TXNL1 protein, corresponding to amino acids 1-289 of Human LGR5.
MW: ~ 32 kDa
Swis Prot.: O43396
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review