TXNL4B polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8720
Background:
Dim2, also known as TXNL4B (thioredoxin-like 4B), or DLP, is a 149 amino acid nuclear protein that exists as a homodimer and plays an essential role in pre-mRNA splicing. Evolutionarily related and sharing 38% sequence identity with Dim1, Dim2 is required for S/G(2) transition during the cell cycle and is able to bind the PRP6 (U5-102K) subunit of the spliceosome. The gene encoding Dim2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Alternative Name:
Thioredoxin-like protein 4B, Dim1-like protein, TXNL4B, DIM2, DLP
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: TXNL4B polyclonal antibody detects endogenous levels of TXNL4B protein.
Immunogen:
Recombinant full length Human TXNL4B.
MW: ~ 17kDa
Swis Prot.: Q9NX01
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Dim2, also known as TXNL4B (thioredoxin-like 4B), or DLP, is a 149 amino acid nuclear protein that exists as a homodimer and plays an essential role in pre-mRNA splicing. Evolutionarily related and sharing 38% sequence identity with Dim1, Dim2 is required for S/G(2) transition during the cell cycle and is able to bind the PRP6 (U5-102K) subunit of the spliceosome. The gene encoding Dim2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Alternative Name:
Thioredoxin-like protein 4B, Dim1-like protein, TXNL4B, DIM2, DLP
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: TXNL4B polyclonal antibody detects endogenous levels of TXNL4B protein.
Immunogen:
Recombinant full length Human TXNL4B.
MW: ~ 17kDa
Swis Prot.: Q9NX01
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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